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La pandémie causée par le nouveau coronavirus, apparu il y a quatre mois en Chine, prend chaque jour un peu plus d’ampleur en Algérie, en effet le bilan du (Covid-19)  établi ce jeudi 23 avril 2020 est de 3007 cas confirmés dont 407 morts, indique jeudi le porte-parole du Comité scientifique de suivi de l’évolution […]

L’article Coronavirus Algérie : Le bilan atteint 3007 cas dont 407 décès- 23 avril 2020 est apparu en premier sur .

Written by Lieve Van Woensel and Mihalis Kritikos with Jens Van Steereghem,

New genetic technologies allow scientists to drastically accelerate the traditional breeding process, thereby achieving in years what previously took centuries. How will this change the way we produce food?

EP

The breeding of plants and animals has been happening ever since the advent of agriculture. It involves selecting individual organisms with desired traits and making them reproduce with other organisms without losing the valuable trait, subsequently using the offspring as new stock from which to select new desirable traits. Over time, the bred organisms develop so many new characteristics that they are markedly different from their wild relatives. The conventional process takes a long time. Breeders have to wait for valuable traits (larger fruit, resistance to disease, more meat, etc.) to arise spontaneously, by extensive screening of crops using classical mutagenesis, or by crossbreeding to utilise the strengths of existing stocks of desired traits.

However, modern genetic techniques can speed up this process. Now, scientists can use the large amounts of genomic data available through DNA sequencing, as well as an increased understanding of molecular biology to determine the traits certain genes engender, and subsequently modify these genes by editing the DNA sequence. Whereas conventional breeders have to wait for the edit of the gene to occur spontaneously, breeders can now introduce the edit with precision. The most popular editing technology currently in use is CRISPR-Cas – a straightforward, efficient and cheap molecular tool that can be programmed to cut specific DNA sequences. It is in repairing these cuts that the sequence can be modified, using the cellular repair mechanisms of the organisms themselves. Scientists can use this method to knock out genes (make them lose their function), edit genes (modify a single pair or a few base pairs, i.e. letters of the DNA code), delete regions of DNA, or add DNA (foreign DNA, referred to as trans/cisgenes). At the moment, the most accessible edits are knock-outs of genes that have a clear correlation to a trait. However, more understanding of gene networks and systems biology, and further optimisation of the technology is likely to lead to more fundamental engineering, changing the biology of agricultural species to produce food with prescribed qualities.

Potential impacts and developments

In plants, research has focused on increasing yields, improving tolerance to biotic and abiotic stress, and biofortification. Biotic stress consists of viral, fungal and bacterial diseases. Abiotic stress can be environmental – relating to cold, salt, drought and nitrogen, or deriving from herbicide exposure. Biofortification increases the nutritional value of the plant. One example is the genetically modified organism (GMO) golden rice, which is enriched with beta-carotene, a precursor of vitamin A. The main species being edited in research are rice, maize, tomato, potato, barley and wheat. Examples include development of a variety of wheat resistant to powdery mildew (a type of fungal disease), enhancement of seed oil composition in camelina, and inhibition of fruit ripening in tomato. It is hoped that many of these CRISPR-Cas edited crops will be part of a transition to a more sustainable form of agriculture.

In animals, research has produced hornless dairy cattle, removing the need for painful dehorning, pigs resistant to classical swine fever virus, and beef cattle with larger muscles, for instance. The example of hornless dairy cattle is one of several initiatives aimed at reducing animal suffering in food production. Other research is geared towards producing beef cattle with male-only offspring and egg-laying hens that lay only female eggs. In both cases offspring of the other sex are now culled because they are not commercially useful.

These engineered plants and animals are only edited, in other words they contain no transgenes, i.e. genes from other species (even though this is possible using CRISPR-Cas). This means that all changes introduced could have occurred by random mutation or classical mutagenesis in conventional breeding. CRISPR-Cas does have the tendency to produce off-target effects, which means edits occasionally occur in other parts of the genome that were not targeted. This is not really a problem, as mutations also occur naturally in organisms, often without effect. Moreover, the edit itself and potential off-targets can be checked by DNA sequencing, allowing the selection of organisms with only the desired edits. Scientists are also working hard to improve the CRISPR-Cas system to reduce off-target effects and make it specific to the targeted sequence.

Policy can determine whether the technology contributes to more sustainable food production or, on the contrary, leads to an unfair distribution of the surplus value resulting from innovative gene editing.

Anticipatory policy-making

Given the rapid pace of scientific developments in the field of gene editing, its regulatory oversight seems more necessary than ever. In February 2017, the European Group on Ethics in Science and New Technologies (EGE) noted that the debate about genome editing should address not only safety, but also broader societal questions, such as justice, equality, proportionality and autonomy. In July 2018, the European Court of Justice (ECJ) ruled that genome-edited organisms qualify as products of genetic engineering and hence fall under the scope of the Deliberate Release Directive 2001/18/EC. According to the ruling, as genome-editing techniques have not yet demonstrated a long safety record in the open field or in a number of applications they cannot be exempted from the rules applying to GMOs.

The Commission is now working with EU Member States and stakeholders to implement the Court’s ruling. In October 2018, the Commission asked the European Union Reference Laboratory for GM Food and Feed (EU-RL GMFF), together with the European Network of GMO Laboratories (ENGL), to draw up a report on the detection of food and feed plant products obtained by new mutagenesis techniques. The report was published in March 2019. It highlights challenges and limitations relating to detection and identification, concluding that products of genome editing can only be readily detected in commodity products if prior knowledge of the altered genome sequence is available. During the 2014-2019 term, the European Parliament objected to every proposed authorisation of genetically modified food and feed, demanding the suspension of all GMO approvals.

In November 2019, the Council asked the European Commission to prepare a study on the status of new genomic techniques under EU law, by 30 April 2021, so as to minimise legal uncertainties in this area. The Commission is currently carrying out targeted consultations with Member States and EU-level stakeholders to gather information for this study. The main question that needs to be addressed is whether products developed using gene editing should be regulated on the basis of the process or the final product’s characteristics, or whether a hybrid approach should be taken.

As food safety is a sensitive matter of primary concern to all Union citizens, any policy initiative in this field should not only be informed by the findings of the Commission study and the respective public consultations, but also be grounded in the principles introduced by Regulation 2019/1381 on the transparency and sustainability of the EU risk assessment in the food chain and the need to accommodate conflicting value frames by broadening the scope of the risk assessment framework and/or by transforming ethical or socio-economic considerations into substantive regulatory standards.

Read this ‘at a glance’ on ‘What if CRISPR became a standard breeding technique?‘ in the Think Tank pages of the European Parliament.

Maghreb-Info - L’Assemblée nationale de Mauritanie veut auditionner l’ancien président mauritanien sur sa gestion du pays pendant ses plus de...

Les députés algériens ont adopté, mercredi 22 avril, un projet de réforme du code pénal « criminalisant » la diffusion de fausses informations qui portent « atteinte à l’ordre public et à la sûreté de l’Etat », un texte contesté par les militants des droits humains. En plein confinement et devant une salle presque vide, […]

L’article Alger criminalise la désinformation contre l’ordre public et l’Etat est apparu en premier sur Afrik.com.

Civil Liberties MEPs backed on Thursday two agreements with Belarus to facilitate the return of persons without the right to stay and the issuance of visas for short trips.
Committee on Civil Liberties, Justice and Home Affairs

Source : © European Union, 2020 - EP

Civil Liberties MEPs backed on Thursday two agreements with Belarus to facilitate the return of persons without the right to stay and the issuance of visas for short trips.
Committee on Civil Liberties, Justice and Home Affairs

Source : © European Union, 2020 - EP

Civil Liberties MEPs backed on Thursday two agreements with Belarus to facilitate the return of persons without the right to stay and the issuance of visas for short trips.
Committee on Civil Liberties, Justice and Home Affairs

Source : © European Union, 2020 - EP

Civil Liberties MEPs backed on Thursday two agreements with Belarus to facilitate the return of persons without the right to stay and the issuance of visas for short trips.
Committee on Civil Liberties, Justice and Home Affairs

Source : © European Union, 2020 - EP

(B2) La France, les Pays-Bas et le Royaume-Uni ont (enfin) décidé « d’unir leurs efforts » dans les Caraïbes face au coronavirus et aux ouragans à venir

Le Karel Doorman à son départ du port de Den Helder vers Saint Martin le 9 avril (crédit : Marine néerlandaise)

La nouvelle a été annoncée aujourd’hui par le ministère français des Armées. Les Néerlandais l’avaient déjà fait il y a deux bonnes semaines (le 9 avril)…

Une réponse militaire coordonnée

Pour les trois pays, il s’agit d’apporter une « réponse militaire coordonnée » en appui aux civils dans la gestion de l’épidémie du coronavirus qui touche aussi les territoires d’outre-mer, mais aussi de contribuer à assurer le maintien de l’ordre (une préoccupation surtout côté néerlandais) et se préparer à la saison des ouragans qui commence dans six semaines (préoccupation britannique).

Une demi-douzaine de navires sur place

Les trois pays ont, en effet, plusieurs moyens sur place : le porte-hélicoptères (ou BPC) Dixmude, côté français ; le navire porte-hélicoptères RFA Argus et le HMS Medway, côté britannique ; le HNLMS Karel Doorman et le HNLMS Zeeland (basé à Curacao), côté néerlandais. L’objectif est d’« optimiser les contributions militaires nationales » et « apporter plus d’agilité et de flexibilité dans la réponse à la propagation du virus à travers les Caraïbes ».

Une coordination établie à Fort de France

Une cellule régionale de coordination militaire conjointe, a été établie à Fort de France, en Martinique. Elle est directement inspirée des « leçons tirées » de la coordination des interventions lors de l’ouragan Irma en 2017, qui avait mis quelque temps à accoucher (lire : Caraïbes. Français, Néerlandais et Britanniques unissent leurs forces. Enfin !). Elle prend appui également sur les discussions menées au sein de l’initiative européenne d’intervention (EI2).

(Nicolas Gros-Verheyde)

Cet article France, Pays-Bas et Royaume-Uni se coordonnent dans les Caraîbes est apparu en premier sur B2 Le blog de l'Europe politique.

Die Lufthansa ist durch die Coronakrise tief in die roten Zahlen geflogen. Der bereinigte Betriebsverlust vergrösserte sich im ersten Quartal auf 1,2 Milliarden Euro. Im Vorjahr hatte die Swiss-Mutter nur ein Defizit von 336 Millionen Euro ausgewiesen.

Roger Federer (38) träumt von einer Fusion der ATP und der WTA. Von vielen erhält er dafür Zuspruch, nur einer äussert Kritik: Bad-Boy Nick Kyrgios (24).

Le verdict du procès en appel de l’ex secrétaire général du FLN Mohamed Djemaï, sera rendu le 29 avril, indique ce jeudi ces avocats. Mis en détention provisoire le 19 septembre 2019, Mohamed Djemaï est poursuivi pour « participation à la destruction de documents de preuves officiels », et « menace d’autrui ». Rédaction d’Algerie360

L’article La date du verdict du procès en appel de Mohamed Djemaï, fixée est apparu en premier sur .

EDA’s Steering Board has green-lit the launch of a new research project aimed at studying ways and means of improving the operational outfit and equipment of Armed Forces operating in extreme cold and icy weather conditions.  

Picture : Austrian Armed Forces

Military missions and operations in cold climate are particularly challenging as they demand from the troops a great deal of physical, operational and mental resilience. Experience from exercises in extreme cold has shown that a considerable number of the soldiers suffer from cold weather injuries (e.g. frostbite, hypothermia, chilblains, immersion foot) and negative energy balance which can highly compromise their performances. An in-depth knowledge of the risk factors for developing cold-related injuries and their impact on the troops’ safety and effectiveness is thus critical to sustain operations in the north.  

Against this backdrop, EDA has just launched a new R&T project to study this problem in greater detail to ascertain consequences and possible countermoves. Under the lead of the Netherlands, three more countries are participating: France, Sweden and Norway (the latter is no formal EDA Member State but has concluded an Administrative Agreement with the Agency). The overall objective is to contribute to improving the European capability of operating in arctic/cold environments by developing tools to reduce the risk of soldiers developing cold-weather-related injuries and enhance war fighter performance.  

The project has a duration of three to four years.
 

New territory

It is the first R&T project in EDA to study Cold Weather Operations on a European level. It will be important to identify the standards and procedures are currently being applied in the various Member States. The project will therefore identify national variations in the regulations and threshold values for body temperature, safe working duration and respective garment requirements and develop an interpretation guide to translate the generic advice of the main existing standard in this field, ISO-11079, and its extension to national clothing & equipment items. It will also review and measure individual variation in thermal stress response and nutritional demands in cold environments. Finally, the intention is also to identify the added value of wearable sensor technologies for improved personalised advice.  

The Cold Weather Operations project is one of several R&T activities under the CapTech CBRN and Human Factors. 
 

More information:

• EDA project page: CapTech CBRN and Human Factors

AMI - Le wali d'Adrar, M. Diagana Mouhamadou El Hadj Wagui, a affirmé que l'état de santé dans la wilaya est stable, Dieu soit loué, et que...

Adrar Info - Le comité ministériel chargé du suivi du dossier Corona a décidé de prolonger la fermeture des établissements scolaires en...

Un inconnu a attaqué une passante dans les rues biennoises dans la nuit de vendredi à samedi dernier. La police recherche des témoins.

Es regnet kaum und die deutschen Landwirte fürchten einen weiteren Dürresommer zusätzlich zur Corona-Pandemie. Man behalte die Situation im Auge, so das Landwirtschaftsministerium, konkrete Maßnahmen sind bislang aber nicht geplant. 

Die gestrige Folge von «Promis unter Palmen» hatte es in sich: Die Hausbewohner mobbten die Luxus-Lady Claudia Obert zu Tränen – bis diese ihre Teilnahme am Format kommentarlos beendete. Desirée Nick findet für die Aktion harte Worte.

Eigentlich darf Marco P.* (44) aus Varese (I) wegen der Ausgangssperre nicht auf die Strasse. Doch der Plättlileger will im Tessin arbeiten. Als ihn eine Patrouille stoppt, gibt er sich als Corona-Held aus. Er postet den Streich online und erntet einen Shitstorm.

Der angeschlagene US-Modekonzern Gap gerät durch die Corona-Krise zunehmend in Finanznöte. Das Unternehmen teilte am Donnerstag mit, Mietzahlungen für seine geschlossenen Filialen in Nordamerika ausgesetzt und weitere Sparmassnahmen beschlossen zu haben.